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4 ways how Single-Use Automation can improve your Bioprocess

As technology advances, the use of single-use automation within bioprocessing has become invaluable. Whilst the initial investment and cost has been viewed as a major hurdle to overcome in the adoption of single-use automation, the ROI has been proven to be rapid and highly beneficial.

Let’s look at the 4 key benefits of automating your process and how single-use automation can help improve your process efficiency and integrity.

1. Reduced Labour Costs and Time Saving

Historically, processes such as normal flow filtration (NFF), tangential-flow filtration (TFF), final fill and chromatography, require teams of operators to monitor and manually maintain the process. This can prove to be both costly and time consuming.

Single-use automation reduces this labour-intensive operation, down to a single operator who sets the automated equipment such as the SciLog single-use pump range with the process parameters. The operator is then free to safely complete other tasks, without risking the integrity of the process. This reduction in labour costs, is one of the areas that automation can really provide ROI.

2. Improved Process Integrity

The main benefit of single-use automation, is the improved level of integrity that can be achieved through a consistent and precise operation. Variation in a process, temperature, inconsistent flow rate or human error, can result in the output being unusable which proves to be a costly and time consuming mistake.

Introducing automation allows the process to be fully-controlled, with programmable flow rates ensuring that the end product is of the optimum quality, whilst single-use sensors can accurately monitor the pressure or temperature.

In addition, with simple set-up and easy-to-use programming functions, automation can significantly reduce the areas where human error can affect a process.

3. Easily Scalable

The accurate programming allows for easy and simple scalability from laboratory through to full-scale production – as offered by the automated TFF system – allowing standardisation to be established throughout. Automation offers a safe, walk-away operation and eliminates the need for constant monitoring, from the smaller clinical trials right the way through to larger production level processing.

4. Speed

Not only can single-use automation ensure product integrity and reduce labour costs, but it proves to provide a faster and less labour-intensive turnaround. The fully programmable operation frees the user to focus on other tasks while the system is running, the automated shut-off allows the process to run to the optimum point, whilst in-built documentation ensures that all the data is securely captured without need for user input.

Every process is different, which is why careful consideration and planning needs to take place to evaluate how automation can best benefit you.

BioPharma Dynamics offer a complete service, using our expert technical knowledge to help integrate automation into your process. Together with our hose and tubing, we can offer a range of transfer sets, fittings, bags, bottles and connectors to create a bespoke solution that fully satisfies your process requirements.

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